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mrc5

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Open main menu Search MRC-5 Language Watch Edit MERS coronavirus particles found in the  lumen  of the  endoplasmic reticulum  in an infected MRC-5 cell MRC-5  ( Medical Research Council  cell strain 5) is a diploid human  cell culture  line composed of  fibroblasts , originally developed from research deriving lung tissue of a 14 week old aborted Caucasian male fetus. [1] [2]  The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach  senescence  in around 45 population doublings. [2] [3] [4] Applications Edit MRC-5 cells are currently used to produce several vaccines including for  MMR ,  varicella  and  polio . [ citation needed ] See also Edit Use of fetal tissue in vaccine development References Edit ^   "MRC-5 (ATCC® CCL-171™)" . Retrieved  2016-05-19 . ^  a   ...