mrc5
Open main menu Search MRC-5 Language Watch Edit MERS coronavirus particles found in the lumen of the endoplasmic reticulum in an infected MRC-5 cell MRC-5 ( Medical Research Council cell strain 5) is a diploid human cell culture line composed of fibroblasts , originally developed from research deriving lung tissue of a 14 week old aborted Caucasian male fetus. [1] [2] The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings. [2] [3] [4] Applications Edit MRC-5 cells are currently used to produce several vaccines including for MMR , varicella and polio . [ citation needed ] See also Edit Use of fetal tissue in vaccine development References Edit ^ "MRC-5 (ATCC® CCL-171™)" . Retrieved 2016-05-19 . ^ a b "AG05965-D Fibroblast from Skin, Lung" . Retrieved 2016-05-19 . ^ Jacobs